Design and Performance Analysis of a Non-Standard EPICS Fast Controller

The large scientific projects present new technological challenges, such as the distributed control over a communication network. In particular, the middleware EPICS is the most extended communication standard in particle accelerators. The integration of modern control architectures in these EPICS networks is becoming common, as for example for the PXI/PXIe and xTCA hardware alternatives. In this work, a different integration procedure for PXIe real time controllers from National Instruments is proposed, using LabVIEW as the design tool. This methodology is considered and its performance is analyzed by means of a set of laboratory experiments. This control architecture is proposed for achieving the implementation requirements of the fast controllers, which need an important amount of computational power and signal processing capability, with a tight real-time demand. The present work studies the advantages and drawbacks of this methodology and presents its comprehensive evaluation by means of a laboratory test bench, designed for the application of systematic tests. These tests compare the proposed fast controller performance with a similar system implemented using an standard EPICS IOC provided by the CODAC system.Comment: This is the extended version of the Conference Record presented in the IEEE Real-Time Conference 2014, Nara, Japan. This paper has been submitted to the IEEE Transactions on Nuclear Scienc

Pavimentos flexibles con rigidez invertida: Caracterización experimental y modelación numérica

La capa granular en un pavimento flexible con rigidez invertida se compacta sobre una base rígida de suelo-cemento y se cubre con una delgada capa asfáltica de rodamiento. A diferencia de los pavimentos convencionales cuya respuesta mecánica depende principalmente de las capas superiores rígidas (asfalto o concreto), la base granular en un pavimento con rigidez invertida desempeña un papel preponderante en la transferencia de cargas inducidas por el tráfico y en la respuesta estructural. Los métodos empíricos de diseño desarrollados para pavimentos convencionales no son apropiados para su análisis. Dada la importancia de la base granular y de su proximidad a la superficie (altos esfuerzos cíclicos), se requirió el desarrollo de nuevos ensayos de laboratorio y de campo para caracterizar la relación entre la rigidez de la base granular y el estado de esfuerzos. Los resultados experimentales se analizan con un modelo constitutivo que emplea el estado del arte en la modelación de bases granulares; el mismo modelo se usa en la simulación numérica de la estructura del pavimento. Los resultados proveen guías preliminares de diseño para pavimentos de rigidez invertida

Determinant factors of long-term performance development in young swimmers

To develop a performance predictor model based on swimmers’ biomechanical profile, relate the partial contribution of the main predictors with the training program, and analyze the time effect, sex effect, and time × sex interaction. 91 swimmers (44 boys, 12.04 ± 0.81 y; 47 girls, 11.22 ± 0.98 y) evaluated during a 3-y period. The decimal age and anthropometric, kinematic, and efficiency features were collected 10 different times over 3 seasons (ie, longitudinal research). Hierarchical linear modeling was the procedure used to estimate the performance predictors. Performance improved between season 1 early and season 3 late for both sexes (boys 26.9% [20.88;32.96], girls 16.1% [10.34;22.54]). Decimal age (estimate [EST] –2.05, P < .001), arm span (EST –0.59, P < .001), stroke length (EST 3.82; P = .002), and propelling efficiency (EST –0.17, P = .001) were entered in the final model. Over 3 consecutive seasons young swimmers’ performance improved. Performance is a multifactorial phenomenon where anthropometrics, kinematics, and efficiency were the main determinants. The change of these factors over time was coupled with the training plans of this talent identification and development program.info:eu-repo/semantics/publishedVersio

Whole transcriptome approach to evaluate the effect of aluminium hydroxide in ovine encephalon

Aluminium hydroxide adjuvants are crucial for livestock and human vaccines. Few studies have analysed their effect on the central nervous system in vivo. In this work, lambs received three different treatments of parallel subcutaneous inoculations during 16 months with aluminium-containing commercial vaccines, an equivalent dose of aluminium hydroxide or mock injections. Brain samples were sequenced by RNA-seq and miRNA-seq for the expression analysis of mRNAs, long non-coding RNAs and microRNAs and three expression comparisons were made. Although few differentially expressed genes were identified, some dysregulated genes by aluminium hydroxide alone were linked to neurological functions, the lncRNA TUNA among them, or were enriched in mitochondrial energy metabolism related functions. In the same way, the miRNA expression was mainly disrupted by the adjuvant alone treatment. Some differentially expressed miRNAs had been previously linked to neurological diseases, oxidative stress and apoptosis. In brief, in this study aluminium hydroxide alone altered the transcriptome of the encephalon to a higher degree than commercial vaccines that present a milder effect. The expression changes in the animals inoculated with aluminium hydroxide suggest mitochondrial disfunction. Further research is needed to elucidate to which extent these changes could have pathological consequences

Simulation of quench detection algorithms for Helmholtz Zentrum Berlin SRF cavities

The Helmholtz Zentrum Berlin is carrying out two accelerator projects which make use of high gradient Continuous Wave CW Superconducting Radiofrequency SRF cavities bERLinPro and BESSY VSR. In both projects, a prompt detection of a quench is crucial to avoid damages in the cryomodules and cavities themselves. In this paper, the response of real time estimation of the cavity parameters using the transmitted and forward RF signals is simulated, in order to perform the quench detection. The time response of the estimated half bandwidth is compared with the dissipated energy in the cavity walls for the different type of SRF cavities used in both projects, i.e., bERLinPro s photoinjector, booster and linac, and BESSY VSR 1.5 GHz and 1.75 GHz cavities. As an intermediate step prior to the implementation in an mTCA.4 system together with the LLRF control and test with a real cavity, the algorithm has been implemented using a National Instruments FPGA board to check its proper behavio

Cardiac Repolarization Abnormalities and Potential Evidence for Loss of Cardiac Sodium Currents on ECGs of Patients with Chagas' Heart Disease

Some individuals with Chagas disease develop right precordial lead ST segment elevation in response to an ajmaline challenge test, and the prevalence of right bundle branch block (RBBB) is also high in Chagas disease. Because these same electrocardiographic abnormalities occur in the Brugada syndrome, which involves genetically defective cardiac sodium channels, acquired damage to cardiac sodium channels may also occur in Chagas disease. We studied several conventional and advanced resting 12-lead/derived Frank-lead ECG parameters in 34 patients with Chagas -related heart disease (mean age 39 14 years) and in 34 age-/gender-matched healthy controls. All ECG recordings were of 5-10 min duration, obtained in the supine position using high fidelity hardware/software (CardioSoft, Houston, TX). Even after excluding those Chagas patients who had resting BBBs, tachycardia and/or pathologic arrhythmia (n=8), significant differences remained in multiple conventional and advanced ECG parameters between the Chagas and control groups (n=26/group), especially in their respective QT interval variability indices, maximal spatial QRS-T angles and low frequency HRV powers (p=0.0006, p=0.0015 and p=0.0314 respectively). In relation to the issue of potential damage to cardiac sodium channels, the Chagas patients had: 1) greater than or equal to twice the incidence of resting ST segment elevation in leads V1-V3 (n=10/26 vs. n=5/26) and of both leftward (n=5/26 versus n=0/26) and rightward (n=7/26 versus n=3/26) QRS axis deviation than controls; 2) significantly increased filtered (40-250 Hz) QRS interval durations (92.1 8.5 versus 85.3 plus or minus 9.0 ms, p=0.022) versus controls; and 3) significantly decreased QT and especially JT interval durations versus controls (QT interval: 387.5 plus or minus 26.4 versus 408.9 plus or minus 34.6 ms, p=0.013; JT interval: 290.5 plus or minus 26.3 versus 314.8 plus or minus 31.3 ms; p=0.0029). Heart rates and Bazett-corrected QTc/JTc intervals were not significantly different between groups. Patients with Chagas heart disease have increased cardiac repolarization abnormalities, especially by advanced ECG. Moreover, as a group, they have decreased uncorrected JT and QT interval durations and increased filtered QRS interval durations (versus age/gender-matched controls), all suggesting a potential loss of cardiac sodium channel function that might be mediated, in part, by cardiac autonomic damage. Overall findings support Brugada et al's recent hypothesis that the pathway leading to sudden death may often be similar in Chagas' disease and Brugada syndrome i.e., damage to the sodium channel (infectious/immunologic/autonomic in Chagas' genetic in Brugada) with consequent loss of sodium currents may facilitate a phase II-reentry based arrhythmic substrate for ventricular fibrillation in both conditions. In general, JT interval-related results have been underreported in the Chagas literature

Melt Inclusion Vapour Bubbles: The Hidden Reservoir for Major and Volatile Elements

Olivine-hosted melt inclusions (MIs) provide samples of magmatic liquids and their dissolved volatiles from deep within the plumbing system. Inevitable post-entrapment modifications can lead to significant compositional changes in the glass and/or any contained bubbles. Re-heating is a common technique to reverse MI crystallisation; however, its effect on volatile contents has been assumed to be minor. We test this assumption using crystallised and glassy basaltic MIs, combined with Raman spectroscopy and 3D imaging, to investigate the changes in fluid and solid phases in the bubbles before and after re-heating. Before re-heating, the bubble contains CO2&nbsp;gas and anhydrite (CaSO4) crystallites. The rapid diffusion of major and volatile elements from the melt during re-heating creates new phases within the bubble: SO2, gypsum, Fe-sulphides. Vapour bubbles hosted in naturally glassy MIs similarly contain a plethora of solid phases (carbonates, sulphates, and sulphides) that account for up to 84% of the total MI sulphur, 80% of CO2, and 14% of FeO. In both re-heated and naturally glassy MIs, bubbles sequester major and volatile elements that are components of the total magmatic budget and represent a “loss” from the glass. Analyses of the glass alone significantly underestimates the original magma composition and storage parameters

Hyperarchiver an Epics Archiver Prototype based on Hypertable

This work started in the context of NSLS2 project at Brookhaven National Laboratory. The NSLS2 control system foresees a very high number of PV variables and has strict requirements in terms of archiving retrieving rate our goal was to store 10K PV sec and retrieve 4K PV sec for a group of 4 signals. The HyperArchiver [1] is an EPICS [2] Archiver implementation engined by Hypertable, an open source database whose internal architecture is derived from Google s Big Table. We discuss the performance of HyperArchiver and present the results of some comparative test